Tocris/LH 846/4896/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/LH 846/4896/10/10 mg

Tocris/LH 846/4896/10/10 mg

商品编号： 4896/10

品牌： Tocris Bioscience

市场价： ¥3300.00

美元价： 1980.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Selectivecaseinkinase1δinhibitor

ChemicalName:N-(5-Chloro-6-methyl-2-benzothiazolyl)benzeneacetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveinhibitorofcaseinkinase(CK)1δ(IC₅₀valuesare290nM,1.3μMand2.5μMforCK1δ,εandα);displaysnoinhibitoryactivityatCK2.InhibitsCK1δ-dependentphosphorylationanddegradationofPER1protein.ShowntolengthenthecircADIanperiodinU2OScells,withminimaleffectonamplitude.

CompoundLibraries

LH846isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	316.81
Formula	C₁₆H₁₃ClN₂OS
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	639052-78-1
PubChemID	851474
InChIKey	DYHAMRNAHTWYKY-UHFFFAOYSA-N
Smiles	O=C(CC3=CC=CC=C3)NC(S2)=NC1=C2C=C(C)C(Cl)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	31.68	100
	ethanol	1.58	5mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight316.81.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.16mL	15.78mL	31.56mL
5mM	0.63mL	3.16mL	6.31mL
10mM	0.32mL	1.58mL	3.16mL
50mM	0.06mL	0.32mL	0.63mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets