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当前位置: 首页 > 产品中心 > kinase > Tocris/LM 22A4/4607/10/10毫克
商品详细Tocris/LM 22A4/4607/10/10毫克
Tocris/LM 22A4/4607/10/10毫克
Tocris/LM 22A4/4607/10/10毫克
商品编号: 4607/10
品牌: Tocris Bioscience
市场价: ¥3580.00
美元价: 2148.00
产地: 美国(厂家直采)
公司:
产品分类: 激酶
公司分类: kinase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentTrkBagoNIST
ChemicalName:N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potenttropomyosin-relatedkinaseB(TrkB)agonist(IC50=47nM).InducesactivationofTrk,AktandERKinmousehippocampusandstriatum.Reversesdeficitsinmotortasklearninginmicefollowingtraumaticbraininjury;restoresrespiratoryfunctioninaratmodelofRettsyndrome.

CompoundLibraries

LM22A4isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt339.34
FormulaC15H21N3O6
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber37988-18-4
PubChemID2054170
InChIKeyRGWJKANXFYJKHN-UHFFFAOYSA-N
SmilesO=C(NCCO)C1=CC(C(NCCO)=O)=CC(C(NCCO)=O)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO33.93100
water33.93100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight339.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.95mL14.73mL29.47mL
5mM0.59mL2.95mL5.89mL
10mM0.29mL1.47mL2.95mL
50mM0.06mL0.29mL0.59mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet