Tocris/LY 333531 hydrochloride/4738/1/1 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/LY 333531 hydrochloride/4738/1/1 mg

Tocris/LY 333531 hydrochloride/4738/1/1 mg

商品编号： 4738/1

品牌： Tocris Bioscience

市场价： ¥3300.00

美元价： 1980.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:ProteinkinaseCinhibitor;selectiveforβisozymes

AlternativeNames:Ruboxistaurin

ChemicalName:(9S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxADIazacyclohexadecine-18,20(19H)-dionehydrochloride

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Isozyme-selectiveinhibitorofproteinkinaseC(PKC);competitivelyandreversIBLyinhibitsPKCβIandPKCβII(IC₅₀valuesare4.7and5.9nMrespectively).SelectiveforPKCβoverotherPKCisozymes(IC₅₀valuesare0.052,0.25,0.30,0.36,0.60and>100μMforPKCη,-δ,-γ,-α,-εand-ζrespectively).ExhibitsselectivityforPKCoverotherATP-dependentkinases,includingproteinkinaseA,caseinkinaseandsrc).

TechnicalData

M.Wt	505.01
Formula	C₂₈H₂₈N₄O₃.HCl
Storage	Storeat-20°C
CASNumber	169939-93-9
PubChemID	9870785
InChIKey	NYQIEYDJYFVLPO-FERBBOLQSA-N
Smiles	O=C(C(C4=CN(CCO[C@H](CN(C)C)CC6)C5=C4C=CC=C5)=C1C2=CN6C3=CC=CC=C23)NC1=O.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	10.1	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight505.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.98mL	9.9mL	19.8mL
5mM	0.4mL	1.98mL	3.96mL
10mM	0.2mL	0.99mL	1.98mL
50mM	0.04mL	0.2mL	0.4mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

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