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Tocris Bioscience(优势品牌)
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当前位置: 首页 > 产品中心 > Receptors > Tocris/LY 344864盐酸盐/2451/10/10 mg
商品详细Tocris/LY 344864盐酸盐/2451/10/10 mg
Tocris/LY 344864盐酸盐/2451/10/10 mg
Tocris/LY 344864盐酸盐/2451/10/10 mg
商品编号: 2451/10
品牌: Tocris Bioscience
市场价: ¥3980.00
美元价: 2388.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Potent,selective5-HT1FagoNIST
ChemicalName:N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selective5-HT1Freceptoragonist(EC50=3nM).Displays>80-foldselectivityoverother5-HTreceptors(Kivaluesare0.006,0.53,0.55,0.56,1.42,1.70,3.50,3.94and4.85μMfor5-HT1F,5-HT1A,5-HT1B,5-HT1D,5-HT1E,5-HT2B,5-HT2C,5-HT2Aand5-HT7receptorsrespectively).Inhibitsneurogenicduralinflammationinvivofollowingi.v.andoraladministration.

LicensingInformation

SoldunderlicensefromEliLillyandCompany

CompoundLibraries

LY344864hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt387.88
FormulaC21H22N3OF.HCl
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber1217756-94-9
PubChemID56972176
InChIKeyOKUHLSYESBLBCP-PKLMIRHRSA-N
SmilesCl[H].CN(C)[C@@H]1CCC2=C(C1)C1=CC(NC(=O)C3=CC=C(F)C=C3)=CC=C1N2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO38.79100
ethanol1.935
water19.3950

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight387.88.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.58mL12.89mL25.78mL
5mM0.52mL2.58mL5.16mL
10mM0.26mL1.29mL2.58mL
50mM0.05mL0.26mL0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet