Tocris/LY 393558/3350/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/LY 393558/3350/10/10 mg

Tocris/LY 393558/3350/10/10 mg

商品编号： 3350/10

品牌： Tocris Bioscience

市场价： ¥3980.00

美元价： 2388.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Dual5-HT_1B/1DantagoNISTand5-HTre-uptakeinhibitor

ChemicalName:1-[2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-1(2H)-pyridinyl]ethyl]-3,4-dihydro-3-(1-methylethyl)-6-(methylsulfonyl)-1H-2,1,3-benzothiADIazine-2,2-dioxide

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Dual5-HT_1B/1Dreceptorantagonist(pK_Bvaluesare9.05and8.98respectively)and5-HTre-uptakeinhibitor(pIC₅₀=8.48).Potentlyantagonizesterminalautoreceptoractivityinvitroandincreasesextracellular5-HTlevelsabovethoseevokedbyfluoxetine(Cat.No.0927)invivo.Alsoactsasanantagonistat5-HT_2Aand5-HT_2Breceptors(pK_ivaluesare7.29and7.35respectively).

TechnicalData

M.Wt	546.68
Formula	C₂₆H₃₁FN₄O₄S₂
Storage	Storeat-20°C
Purity	≥97%(HPLC)
CASNumber	271780-64-4
PubChemID	10347428
InChIKey	QUSLYAPLTMMCFE-UHFFFAOYSA-N
Smiles	CC(C)N2S(N(CCN3CC=C(C4=CNC5=C4C=CC(F)=C5)CC3)C1=CC=C(S(=O)(C)=O)C=C1C2)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	54.67	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight546.68.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.83mL	9.15mL	18.29mL
5mM	0.37mL	1.83mL	3.66mL
10mM	0.18mL	0.91mL	1.83mL
50mM	0.04mL	0.18mL	0.37mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

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