Tocris/Leflunomide/2228/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Leflunomide/2228/50/50 mg

Tocris/Leflunomide/2228/50/50 mg

商品编号： 2228/50

品牌： Tocris Bioscience

市场价： ¥1900.00

美元价： 1140.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Dihydroorotatedehydrogenaseinhibitor

AlternativeNames:HWA486,RS-34821

ChemicalName:5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofdihydroorotatedehydrogenase(IC₅₀=2.5μM).InhibitsdenovopyrimidinesynthesisinhumanTcellsinvitro;alsoinhibitslymphocyteproliferation.Exhibitsefficacyinseveralanimalmodelsofautoimmunedisease,arthritisandgraftrejection.Activemetabolite,teriflunomide(A771726,Cat.No.5069),alsoavailable.

TechnicalData

M.Wt	270.21
Formula	C₁₂H₉F₃N₂O₂
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	75706-12-6
PubChemID	3899
InChIKey	VHOGYURTWQBHIL-UHFFFAOYSA-N
Smiles	CC1=C(C=NO1)C(=O)NC1=CC=C(C=C1)C(F)(F)F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	27.01	100
	ethanol	27.01	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight270.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.7mL	18.5mL	37.01mL
5mM	0.74mL	3.7mL	7.4mL
10mM	0.37mL	1.85mL	3.7mL
50mM	0.07mL	0.37mL	0.74mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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