Tocris/Linopirdine dihydrochloride/1999/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Linopirdine dihydrochloride/1999/10/10 mg

Tocris/Linopirdine dihydrochloride/1999/10/10 mg

商品编号： 1999/10

品牌： Tocris Bioscience

市场价： ¥3500.00

美元价： 2100.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:K_V7(KCNQ)channelblocker

AlternativeNames:DuP996

ChemicalName:1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-onedihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

BlockerofK_V7(KCNQ)voltage-gatedpotassiumchannels;blocksK_V7.1+7.3(KCNQ2+3)/M-currents(IC₅₀=4-7μM)andK_V7.1(KCNQ1)homomericchannels(IC₅₀=8.9μM).AugmentshippocampalAChreleaseandisacognitiveenhancerfollowingoraladmiNISTrationinvivo.

CompoundLibraries

LinopirdinedihydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	464.39
Formula	C₂₆H₂₁N₃O.2HCl
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	113168-57-3
PubChemID	14209557
InChIKey	ZEVVHCGTTNRYOY-UHFFFAOYSA-N
Smiles	Cl.Cl.O=C1N(C2=CC=CC=C2C1(CC1=CC=NC=C1)CC1=CC=NC=C1)C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	46.44	100
	ethanol	46.44	100
	water	46.44	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight464.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.15mL	10.77mL	21.53mL
5mM	0.43mL	2.15mL	4.31mL
10mM	0.22mL	1.08mL	2.15mL
50mM	0.04mL	0.22mL	0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets