Tocris/Lomeguatrib/4359/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Lomeguatrib/4359/10/10 mg

Tocris/Lomeguatrib/4359/10/10 mg

商品编号： 4359/10

品牌： Tocris Bioscience

市场价： ¥4500.00

美元价： 2700.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:MGMTinhibitor

AlternativeNames:PaTrin-2

ChemicalName:6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofO⁶-methylguanine-DNAmethyltransferase(MGMT);(IC₅₀=0.009μMincell-freeextractsfromHeLaS3cells);attenuatesMGMTactivityinvitroandinvivo.Enhancestheantitumoractivityoftemozolomide(Cat.No.2706)inbothhumanmelanomaandMCF-7xenografts.

CompoundLibraries

LomeguatribisalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	326.17
Formula	C₁₀H₈BrN₅OS
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	192441-08-0
PubChemID	3025944
InChIKey	JUJPKFNFCWJBCX-UHFFFAOYSA-N
Smiles	NC1=NC(OCC3=CC(Br)=CS3)=C2C(N=CN2)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	32.62	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight326.17.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.07mL	15.33mL	30.66mL
5mM	0.61mL	3.07mL	6.13mL
10mM	0.31mL	1.53mL	3.07mL
50mM	0.06mL	0.31mL	0.61mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

PreparingStockSolutions

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