Tocris/M 25/4917/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/M 25/4917/50/50毫克

Tocris/M 25/4917/50/50毫克

商品编号： 4917/50

品牌： Tocris Bioscience

市场价： ¥16500.00

美元价： 9900.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentSmoothened(Smo)receptorantagoNIST

ChemicalName:N-[[1-(2-Methoxyphenyl)-1H-indazol-5-yl]methyl]-2-propylpentanamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentSmoothened(Smo)receptorantagonist(IC₅₀=5nM).InhibitstheHedgehogsignalingpathway.InhibitsShhinducedGliluciferasereporteractivityinShh-light2cells(IC₅₀=5nM).AntagonizesGSA-10andSAG-mediateddifferentiationoftheC3H10T1/2cellline(IC₅₀valuesare69and115nM,respectively).

CompoundLibraries

M25isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	379.5
Formula	C₂₃H₂₉N₃O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
PubChemID	44250034
InChIKey	WATNXVHKRRTUFK-UHFFFAOYSA-N
Smiles	O=C(C(CCC)CCC)NCC1=CC=C(N(C3=CC=CC=C3OC)N=C2)C2=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	37.95	100
	ethanol	37.95	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight379.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.64mL	13.18mL	26.35mL
5mM	0.53mL	2.64mL	5.27mL
10mM	0.26mL	1.32mL	2.64mL
50mM	0.05mL	0.26mL	0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets