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商品详细Tocris/3-MATIDA/2196/10/10 mg

Tocris/3-MATIDA/2196/10/10 mg

商品编号： 2196/10

品牌： Tocris Bioscience

市场价： ¥3980.00

美元价： 2388.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potent,selectivemGlu₁antagoNIST

ChemicalName:α-Amino-5-carboxy-3-methyl-2-thiopheneaceticacid

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentmetabotropicglutamatemGlu₁receptorantagonist(IC₅₀=6.3μMatratmGlu_1a).Displays≥40-foldselectivityoverotherreceptors:mGlu₅,mGlu₂,mGlu_4a(IC₅₀>300μM),NMDAandAMPA(IC₅₀=250μM).Neuroprotectiveinculturedmurinecorticalcellsandrathippocampalsliceculturesinvitro.Reducesthevolumeofischemia-inducedbraininfarctsinratsfollowingsystemicadministrationinvivo.

TechnicalData

M.Wt	215.23
Formula	C₈H₉NO₄S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	518357-51-2
PubChemID	10398360
InChIKey	KOMWRBFEDDEWEP-UHFFFAOYSA-N
Smiles	CC1=C(SC(=C1)C(O)=O)C(N)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.NaOH	21.52	100
	DMSO	10.76	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight215.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	4.65mL	23.23mL	46.46mL
5mM	0.93mL	4.65mL	9.29mL
10mM	0.46mL	2.32mL	4.65mL
50mM	0.09mL	0.46mL	0.93mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

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