BiologicalActivity
SelectiveinhibitorofclassIIahistonedeacetylases(HDACs).Exhibitstissue-selectiveinhibitionbetweenmembersofclassIIdeacetylasesinvivo;inhibitsHDAC4andHDAC5inskeletalmuscleandtheheartwithoutaffectingHDAC3activity.ArrestsmyogenesisthroughthestABIlizationofmyocyteenhancerfactor2D(MEF2D)-HDAC3/4complex.DisplaysnoinhibitionofclassIHDACactivityorexpression.
CompoundLibraries
MC1568isalsoofferedaspartoftheTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 314.31 |
| Formula | C17H15FN2O3 |
| Storage | Storeat+4°C |
| Purity | ≥96%(HPLC) |
| CASNumber | 852475-26-4 |
| PubChemID | 11381449 |
| InChIKey | QRDAPCMJAOQZSU-KQQUZDAGSA-N |
| Smiles | CN1C=C(/C=C/C(C2=CC(F)=CC=C2)=O)C=C1/C=C/C(NO)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.43 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight314.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.18mL | 15.91mL | 31.82mL |
| 5mM | 0.64mL | 3.18mL | 6.36mL |
| 10mM | 0.32mL | 1.59mL | 3.18mL |
| 50mM | 0.06mL | 0.32mL | 0.64mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
本网站将在规定时间内给予删除等相关处理。
