Tocris/MG 132/1748/5/5 MG-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/MG 132/1748/5/5 MG

Tocris/MG 132/1748/5/5 MG

商品编号： 1748/5

品牌： Tocris Bioscience

市场价： ¥2580.00

美元价： 1548.00

产地：美国(厂家直采)

公司：

产品分类：蛋白酶类

公司分类： protease

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Proteasomeandcalpaininhibitor.InhibitsNF-κBactivation

AlternativeNames:Z-LLL-al,Z-Leu-Leu-Leu-CHO

ChemicalName:N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide

Purity:≥95%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentcell-permeableinhibitorofproteasome(IC₅₀=100nM)andcalpain(IC₅₀=1.2μM).InhibitsTNF-α-inducedNF-κBactivationandIκBαdegradation.InducesneuriteoutgrowthinPC12cellsandhasanticancerpropertiesinvitro.

TechnicalData

M.Wt	475.63
Formula	C₂₆H₄₁N₃O₅
Storage	Storeat-20°C
Purity	≥95%(HPLC)
CASNumber	133407-82-6
PubChemID	90488707
InChIKey	AUQBNOXQYSNYAH-OJSMNCEXSA-N
Smiles	[H]C(C)C[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)N[C@@H](CC(C)C)C(C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	47.56	100
	ethanol	47.56	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight475.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.1mL	10.51mL	21.02mL
5mM	0.42mL	2.1mL	4.2mL
10mM	0.21mL	1.05mL	2.1mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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TechnicalData

SolubilityData

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