Tocris/MI 2二氢氯化物/4707/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/MI 2二氢氯化物/4707/10/10 mg

Tocris/MI 2二氢氯化物/4707/10/10 mg

商品编号： 4707/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Menin-MLLinteractioninhibitor

ChemicalName:4-[4-(4,5-Dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propylthieno[2,3-d]pyrimidinedihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Menin-MLLinteractioninhibitor;bindsmenin(IC₅₀=446nM).SelectivelyinhibitsproliferationandinducesapoptosisofleukemiacellsharboringMLLfusionproteins.AlsoblockstransformationandinduceshematopoieticdifferentiationofMLL-AF9transformedbonemarrowcells.

TechnicalData

M.Wt	448.48
Formula	C₁₈H₂₅N₅S₂.2HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
PubChemID	6436801
InChIKey	OJCKRNPLOZHAOU-UGKRXNSESA-N
Smiles	CCCC2=CC1=C(N3CCN(C4=NCC(C)(C)S4)CC3)N=CN=C1S2.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	44.85	100
	water	22.42	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight448.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.23mL	11.15mL	22.3mL
5mM	0.45mL	2.23mL	4.46mL
10mM	0.22mL	1.11mL	2.23mL
50mM	0.04mL	0.22mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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