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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/MIRA-1/3362/10/10 mg
商品详细Tocris/MIRA-1/3362/10/10 mg
Tocris/MIRA-1/3362/10/10 mg
Tocris/MIRA-1/3362/10/10 mg
商品编号: 3362/10
品牌: Tocris Bioscience
市场价: ¥2180.00
美元价: 1308.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Restoresmutantp53activity;proapoptotic
ChemicalName:1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Restoreswild-typeconformation,functionandDNAbindingactivitytomutantp53.Inducesp53transcriptionaltransactivationofp21,MDM2andPUMA,andpromotestumorcelldeathbyapoptosisinamutantp53-dependentmannerinvitro(IC50=10μM).

TechnicalData

M.Wt183.16
FormulaC8H9NO4
StorageStoreat+4°C
CASNumber72835-26-8
PubChemID227681
InChIKeyYXEWPGYLMHXLPS-UHFFFAOYSA-N
SmilesO=C(N1COC(CC)=O)C=CC1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO18.32100
ethanol18.32100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight183.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM5.46mL27.3mL54.6mL
5mM1.09mL5.46mL10.92mL
10mM0.55mL2.73mL5.46mL
50mM0.11mL0.55mL1.09mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet