Tocris/ML 240/5153/10/10 mg-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > Other_enzymes > Tocris/ML 240/5153/10/10 mg

商品详细Tocris/ML 240/5153/10/10 mg

Tocris/ML 240/5153/10/10 mg

商品编号： 5153/10

品牌： Tocris Bioscience

市场价： ¥3700.00

美元价： 2220.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:ATP-competitiveinhibitorofp97ATPase

ChemicalName:2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ATP-competitiveinhibitorofp97ATPase(VCP,IC₅₀=110nM).ExhibitsantiproliferativeactivityinNCI-60cancercelllinesandrapidlyinducesexecutionercaspases3and7inmultiplecoloncancercells.PromotesaccumulationofLC3-IIandimpairsautophagosomematuration.Alsoimpairstheendoplasmic-reticulum-associateddegradation(ERAD)pathway.

TechnicalData

M.Wt	396.44
Formula	C₂₃H₂₀N₆O
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	1346527-98-7
PubChemID	49830258
InChIKey	NHAMBLRUUJAFOY-UHFFFAOYSA-N
Smiles	NC1=NC4=C(C=CC=C4)N1C3=NC2=C(OC)C=CC=C2C(NCC5=CC=CC=C5)=N3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	7.93	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight396.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.52mL	12.61mL	25.22mL
5mM	0.5mL	2.52mL	5.04mL
10mM	0.25mL	1.26mL	2.52mL
50mM	0.05mL	0.25mL	0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

Selectanotherlanguage:

BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets