Tocris/ML 277/4777/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/ML 277/4777/10/10 mg

Tocris/ML 277/4777/10/10 mg

商品编号： 4777/10

品牌： Tocris Bioscience

市场价： ¥3980.00

美元价： 2388.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveK_v7.1(KCNQ1)potassiumchannelactivator;augmentsI_Kscurrent

ChemicalName:(2R)-N-[4-(4-Methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveK_v7.1(KCNQ1)potassiumchannelactivator(EC₅₀=260nM).Exhibits>100-foldselectivityversusKCNQ2,KCNQ4andhERGpotassiumchannels.AugmentsI_Kscurrentofculturedhumancardiomyocytesandshortensactionpotentialduration.

CompoundLibraries

ML277isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	471.59
Formula	C₂₃H₂₅N₃O₄S₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1401242-74-7
PubChemID	53347902
InChIKey	OXQNLLVUVDAEHC-OAQYLSRUSA-N
Smiles	O=[C@@]([C@H]3CCCCN3S(C4=CC=C(C)C=C4)(=O)=O)NC1=NC(C2=CC=C(OC)C=C2)=CS1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	47.16	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight471.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.12mL	10.6mL	21.2mL
5mM	0.42mL	2.12mL	4.24mL
10mM	0.21mL	1.06mL	2.12mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets