Tocris/ML 281/4880/10/10mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/ML 281/4880/10/10mg

Tocris/ML 281/4880/10/10mg

商品编号： 4880/10

品牌： Tocris Bioscience

市场价： ¥3900.00

美元价： 2340.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:STK33inhibitor

ChemicalName:N-[2-(3,4-Dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-2-thiophenecarboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitoroftheserine/threoninekinaseSTK33(IC₅₀=14nM).Exhibits>700-foldselectivityforSTK33overthestructurallyrelatedproteinkinaseA(PKA);alsoexhibits550-foldselectivityoverAurorakinaseB.

CompoundLibraries

ML281isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	389.47
Formula	C₂₂H₁₉N₃O₂S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1404437-62-2
PubChemID	53377448
InChIKey	HWOYIOLMBQSTQS-UHFFFAOYSA-N
Smiles	CC(C)C1=CC(C2=NC(C=CC=C3)=C3NC2=O)=C(NC(C4=CC=CS4)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	38.95	100
	ethanol	3.89	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight389.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.57mL	12.84mL	25.68mL
5mM	0.51mL	2.57mL	5.14mL
10mM	0.26mL	1.28mL	2.57mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets