BiologicalActivity
Kainicacid(Cat.No.0222)cagedwiththephotosensitive4-methoxy-7-nitroindolinylgroup.GenerateslargeinwardcurrentsatrestingmembranepotentialuponwidefieldphotolysisinPurkinjeneurons.SelectivelyphotoactivateskainatereceptorswhenusedinconjunctionwithanAMPAantagoNIST,suchasGYKI53655(Cat.No.2555).Suitableforuncagingwith300-380nmexcitation.Exhibitsrapiduncagingraterelativetoionotropicglutamatereceptoractivation.Alsosuitablefortwo-photonuncagingexperimentsat720nm.
LicensingInformation
SoldunderlicencefromtheMedicalResearchCouncil
TechnicalData
| M.Wt | 389.4 |
| Formula | C19H23N3O6 |
| Storage | Storeat-20°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 1315378-75-6 |
| PubChemID | 57414719 |
| InChIKey | IQGCUMUIYXHZOT-AHIWAGSCSA-N |
| Smiles | C=[C@@](C)[C@@H]1[C@H](CC(N2C(C([N+]([O-])=O)=CC=C3OC)=C3CC2)=O)[C@@H]([C@](O)=O)NC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 38.94 | 100 | |
| water | 1.95 | 5mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight389.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.57mL | 12.84mL | 25.68mL |
| 5mM | 0.51mL | 2.57mL | 5.14mL |
| 10mM | 0.26mL | 1.28mL | 2.57mL |
| 50mM | 0.05mL | 0.26mL | 0.51mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
本网站将在规定时间内给予删除等相关处理。
