Biological Activity
Potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.
Technical Data
| M. Wt | 626.33 |
| Formula | C15H22N2Na2O16P2S |
| Storage | Desiccate at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 15039-58-4 |
| PubChem ID | 73755042 |
| InChI Key | TYVFMVSNSGMZPA-QBNUFUENSA-L |
| Smiles | [Na+].[Na+].OC[C@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=S)[C@H](O)[C@@H](O)[C@@H]1O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 62.63 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 626.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.6 mL | 7.98 mL | 15.97 mL |
| 5 mM | 0.32 mL | 1.6 mL | 3.19 mL |
| 10 mM | 0.16 mL | 0.8 mL | 1.6 mL |
| 50 mM | 0.03 mL | 0.16 mL | 0.32 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Ko et al (2007) Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J.Med.Chem. 50 2030 PMID: 17407275
Keywords: MRS 2690, supplier, Potent, P2Y14, agonists, Receptors, Purinergic, purinoceptors, MRS2690, Purinergic, P2Y, Receptors, Purinergic, P2Y, Receptors, Tocris Bioscience
