Biological Activity
Potent and selective PRMT4 and PRMT6 inhibitor.
Licensing Information
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the MS049 probe summary on the SGC website.
Technical Data
| M. Wt | 338.4 |
| Formula | C15H24N2O.C2H2O4 |
| Storage | Desiccate at RT |
| Purity | ≥98% (HPLC) |
| PubChem ID | 121513883 |
| InChI Key | RWKUVRQLFRJTTR-UHFFFAOYSA-N |
| Smiles | CNCCN(CC2)CCC2OCC1=CC=CC=C1.OC(C(O)=O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 6.77 | 20 | |
| water | 33.84 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 338.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.96 mL | 14.78 mL | 29.55 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.91 mL |
| 10 mM | 0.3 mL | 1.48 mL | 2.96 mL |
| 50 mM | 0.06 mL | 0.3 mL | 0.59 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Shen et al (2016) Discovery of a potent, selective, and cell-active dual inhibitor of protein arginine methyltransferase 4 and protein arginine methyltransferase 6. J.Med.Chem. 59 9124 PMID: 27584694
Keywords: MS049 oxalate salt, supplier, PRMT4, PRMT6, protein, arginine, methyltransferases, inhibits, inhibitors, 1502816-23-0, Protein, Arginine, Methyltransferases, Protein, Arginine, Methyltransferases, Tocris Bioscience
