Biological Activity
Centrally active opioid analgesic. Partial agonist at the μ1 opioid receptor. Also shown to inhibit acetylcholinesterase.
Compound Libraries
Meptazinol hydrochloride is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 269.81 |
| Formula | C15H23NO.HCl |
| Storage | Desiccate at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 59263-76-2 |
| PubChem ID | 65483 |
| InChI Key | MPJUSISYVXABBH-UHFFFAOYSA-N |
| Smiles | OC1=CC=CC(C2(CC)CN(C)CCCC2)=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.24 | 75 | |
| ethanol | 26.98 | 100 | |
| water | 26.98 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 269.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.71 mL | 18.53 mL | 37.06 mL |
| 5 mM | 0.74 mL | 3.71 mL | 7.41 mL |
| 10 mM | 0.37 mL | 1.85 mL | 3.71 mL |
| 50 mM | 0.07 mL | 0.37 mL | 0.74 mL |
Molarity Calculator
Reconstitution Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Spiegel and Pasternak (1984) Meptazinol: a novel Mu-1 selective opioid analgesic. J.Pharmacol.Exp.Ther. 228 414 PMID: 6141283
Galli et al (1996) Reversible inhibition of cholinesterases by opioids: possible pharmacological consequences. J.Pharm.Pharmacol. 48 116 PMID:
Keywords: Meptazinol hydrochloride, supplier, Partial, agonists, μ1-opioid, mu1-opioid, Receptors, MOP, OP3, μ-opioid, mu-opioid, Mu, Opioid, Receptors, Mu, Opioid, Receptors, Tocris Bioscience
