Biological Activity
5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites.
Technical Data
| M. Wt | 459.45 |
| Formula | C14H17N3.(C4H4O4)2 |
| Storage | Store at RT |
| CAS Number | 171205-17-7 |
| PubChem ID | 11957670 |
| InChI Key | HNSITEGFVDCKMF-SPIKMXEPSA-N |
| Smiles | OC(=O)C=C/C(O)=O.OC(=O)C=C/C(O)=O.CN1CCN(CC1)C1=NC2=C(C=CC=C2)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 50 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 459.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.18 mL | 10.88 mL | 21.77 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.35 mL |
| 10 mM | 0.22 mL | 1.09 mL | 2.18 mL |
| 50 mM | 0.04 mL | 0.22 mL | 0.44 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Glennon et al (1989) Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study. Eur.J.Pharmacol. 168 387 PMID: 2583244
Keywords: N-Methylquipazine dimaleate, supplier, 5-HT3, agonists, Serotonin, Receptors, 5-HT3, Receptors, 5-HT3, Receptors, Tocris Bioscience
