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商品详细Tocris/Mevastatin/1526/50/50 mg

Tocris/Mevastatin/1526/50/50 mg

商品编号： 1526/50

品牌： Tocris Bioscience

市场价： ¥9180.00

美元价： 5508.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:HMG-CoAreductaseinhibitor

AlternativeNames:Compactin

ChemicalName:(2S)-2-Methyl-(1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenylbutanoate

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofHMG-CoAreductase;decreasescholesterolbiosynthesis,invitroandinvivo.Inducesapoptosis,arrestscancercellsinG1phaseanddownregulatescdk2,4,and6,cyclinD1andE1,p21andp27.Inactivelactamprodrugofmevastatinhydroxyacid,naturallybioactivatedinvivofollowingoraladmiNISTration.

CompoundLibraries

MevastatinisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	390.52
Formula	C₂₃H₃₄O₅
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	73573-88-3
PubChemID	64715
InChIKey	AJLFOPYRIVGYMJ-INTXDZFKSA-N
Smiles	[H][C@@]12C(C=C[C@H](C)[C@@]([H])2CC[C@@]3([H])OC(C[C@]([H])(O)C3)=O)=CCC[C@@H]1OC([C@@H](C)CC)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	19.53	50mMwithgentlewarming
	ethanol	9.76	25mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight390.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.56mL	12.8mL	25.61mL
5mM	0.51mL	2.56mL	5.12mL
10mM	0.26mL	1.28mL	2.56mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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