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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/Mirin/3190/50/50 mg
商品详细Tocris/Mirin/3190/50/50 mg
Tocris/Mirin/3190/50/50 mg
Tocris/Mirin/3190/50/50 mg
商品编号: 3190/50
品牌: Tocris Bioscience
市场价: ¥12580.00
美元价: 7548.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:MRN-ATMpathwayinhibitor
ChemicalName:Z-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Mre11-Rad50-Nbs1(MRN)-ATMpathwayinhibitorthatblocksthe3'and5'exonucleaseactivityassociatedwithMre11.PreventsATMactivationinresponsetodoublestrandbreaks(IC50=12μM)andinducesG2cellcyclearrest.Alsoblockshomology-directedrepairinvitro.

CompoundLibraries

MirinisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt220.25
FormulaC10H8N2O2S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber1198097-97-0
PubChemID1206243
InChIKeyYBHQCJILTOVLHD-YVMONPNESA-N
SmilesOC(C=C1)=CC=C1/C=C2/C(NC(S2)=N)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.02100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight220.25.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.54mL22.7mL45.4mL
5mM0.91mL4.54mL9.08mL
10mM0.45mL2.27mL4.54mL
50mM0.09mL0.45mL0.91mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet