Biological Activity
Reversible monoamine oxidase A (MOA-A) inhibitor.
Compound Libraries
Moclobemide is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 268.74 |
| Formula | C13H17ClN2O2 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 71320-77-9 |
| PubChem ID | 4235 |
| InChI Key | YHXISWVBGDMDLQ-UHFFFAOYSA-N |
| Smiles | O=C(NCCN2CCOCC2)C1=CC=C(Cl)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 26.87 | 100 | |
| ethanol | 26.87 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 268.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.72 mL | 18.61 mL | 37.21 mL |
| 5 mM | 0.74 mL | 3.72 mL | 7.44 mL |
| 10 mM | 0.37 mL | 1.86 mL | 3.72 mL |
| 50 mM | 0.07 mL | 0.37 mL | 0.74 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Merck Index 12 6309 PMID:
Burkard et al (1989) Pharmacological profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A. J.Pharmacol.Exp.Ther. 248 391 PMID: 2913284
Prada et al (1989) Neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A. J.Pharmacol.Exp.Ther. 248 400 PMID: 2783611
Keywords: Moclobemide, supplier, reversible, monoamine, oxidase, a, moa-a, inhibitors, inhibits, Monoamine, Oxidase, Adrenergic, Related, Compounds, Dopaminergic-Related, 5-HT-Related, 5-HT3, Receptors, Monoamine, Oxidase, Tocris Bioscience
