Tocris/Monastrol/1305/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Monastrol/1305/50/50 mg

Tocris/Monastrol/1305/50/50 mg

商品编号： 1305/50

品牌： Tocris Bioscience

市场价： ¥14100.00

美元价： 8460.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveinhibitorofmitotickinesinEg5

ChemicalName:1,2,3,4-Tetrahydro-4-(3-hydroxyphenyl)-6-methyl-2-thioxo-5-pyrimidinecarboxylicacid,ethylester

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,cell-permeable,smallmoleculemitosisinhibitorthatdoesnotinteractwithtubulin.ArrestscellsinmitosisandspecificallyinhibitsthemotilityofthemitotickinesinEg5,amotorproteinrequiredformitoticspindleformationandmaintenance(IC₅₀=14μM).

LicensingInformation

SoldwiththepermissionofHarvardUniversity

CompoundLibraries

MonastrolisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	292.35
Formula	C₁₄H₁₆N₂O₃S
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	254753-54-3
PubChemID	5353454
InChIKey	UAIYNMRLUHHRMF-AATRIKPKSA-N
Smiles	CCOC(=O)C1=C(C)NC(=S)NC1C1=CC(O)=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	29.24	100
	ethanol	5.85	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight292.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.42mL	17.1mL	34.21mL
5mM	0.68mL	3.42mL	6.84mL
10mM	0.34mL	1.71mL	3.42mL
50mM	0.07mL	0.34mL	0.68mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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