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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Receptors > Tocris/NAS-181/1413/50/50 mg
商品详细Tocris/NAS-181/1413/50/50 mg
Tocris/NAS-181/1413/50/50 mg
Tocris/NAS-181/1413/50/50 mg
商品编号: 1413/50
品牌: Tocris Bioscience
市场价: ¥18500.00
美元价: 11100.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Selectiver5-HT1BantagoNIST.Activeinvivo
ChemicalName:(2R)-2-[[[3-(4-Morpholinylmethyl)-2H-1-benzopyran-8-yl]oxy]methyl]morpholinedimethanesulfonate
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveantagonistattherat5-HT1Breceptor(Ki=47nM).Increasessynthesisandmetabolismof5-HTinthebrainfollowingsystemicadministrationandimprovespassiveavoidanceretentionperformanceinvivo.Increasessubthalamicnucleus-triggeredcomplexEPSCsandburstfiringinSNrGABAneurons

TechnicalData

M.Wt538.63
FormulaC19H26N2O4.2CH3SO3H
StorageDesiccateat-20°C
Purity≥97%(HPLC)
CASNumber1217474-40-2
PubChemID90479790
InChIKeyVCIPBXUEKWCJAU-DZYJZKBLSA-N
SmilesCS(=O)(O)=O.CS(=O)(O)=O.N1(CC2=CC3=C(C(OC[C@H]4CNCCO4)=CC=C3)OC2)CCOCC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
phosphatebufferedsaline53.86100
DMSO53.86100
water53.86100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight538.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.86mL9.28mL18.57mL
5mM0.37mL1.86mL3.71mL
10mM0.19mL0.93mL1.86mL
50mM0.04mL0.19mL0.37mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet