Tocris/PF 04991532/6345/25/25 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PF 04991532/6345/25/25 mg

Tocris/PF 04991532/6345/25/25 mg

商品编号： 6345/25

品牌： Tocris Bioscience

市场价： ¥6180.00

美元价： 3708.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potenthepatoselectiveglucokinaseactivator

ChemicalName:6-[[(2S)-3-Cyclopentyl-1-oxo-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propyl]amino]-3-pyridinecarboxylicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potenthepatoselectiveglucokinaseactivator(EC₅₀=90nM).Exhibits>50-foldlivertopancreasratiooftissuedistribution.Reducesfastingandpostprandialglucoselevelswithnohypoglycemiainaratdiabetesmodel.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt	396.36
Formula	C₁₈H₁₉F₃N₄O₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1215197-37-7
PubChemID	46181428
InChIKey	GKMLFBRLRVQVJO-ZDUSSCGKSA-N
Smiles	O=C(NC1=CC=C(C(O)=O)C=N1)[C@@H](N2C=NC(C(F)(F)F)=C2)CC3CCCC3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	39.64	100
	ethanol	39.64	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight396.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.52mL	12.61mL	25.23mL
5mM	0.5mL	2.52mL	5.05mL
10mM	0.25mL	1.26mL	2.52mL
50mM	0.05mL	0.25mL	0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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