Tocris/NF 023/1240/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/NF 023/1240/10/10 mg

Tocris/NF 023/1240/10/10 mg

商品编号： 1240/10

品牌： Tocris Bioscience

市场价： ¥3180.00

美元价： 1908.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Selective,competitiveP2X₁antagoNIST

ChemicalName:8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonicacid,hexasodiumsalt

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Asubtype-selective,competitiveandreversIBLeP2X₁receptorantagonist.DisplaysIC₅₀valuesof0.21,28.9,>50and>100μMforhumanP2X₁,P2X₃,P2X₂,andP2X₄-mediatedresponsesrespectively.Selectiveoveradrenoceptors,histamineandP2Yreceptors.Alsoselectivelyinhibitstheα-subunitofG_o/i(EC₅₀~300nM).

TechnicalData

M.Wt	1162.86
Formula	C₃₅H₂₀N₄Na₆O₂₁S₆
Storage	DesiccateatRT
CASNumber	104869-31-0
PubChemID	4465
InChIKey	FMQURVHYTBGYSQ-UHFFFAOYSA-H
Smiles	[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)C1=CC2=C(C=CC(NC(=O)C3=CC=CC(NC(=O)NC4=CC(=CC=C4)C(=O)NC4=C5C(C=C(C=C5S([O-])(=O)=O)S([O-])(=O)=O)=C(C=C4)S([O-])(=O)=O)=C3)=C2C(=C1)S([O-])(=O)=O)S([O-])(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto100mMinwater

Solubility

Solubleto100mMinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1162.86.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.86mL	4.3mL	8.6mL
5mM	0.17mL	0.86mL	1.72mL
10mM	0.09mL	0.43mL	0.86mL
50mM	0.02mL	0.09mL	0.17mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets