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商品详细Tocris/NGB 2904/2635/50/50 mg

Tocris/NGB 2904/2635/50/50 mg

商品编号： 2635/50

品牌： Tocris Bioscience

市场价： ¥15300.00

美元价： 9180.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveD₃antagoNIST

ChemicalName:N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivedopamineD₃receptorantagonist(K_ivaluesare1.4,217,223,642,>5000,>10000and>10000nMforD₃,D₂,5-HT₂,α₁,D₄,D₁andD₅receptorsrespectively).Potentlyantagonizesquinpirole-stimulatedmitogenesis(IC₅₀=6.8nM).Attenuatescocaine'srewardingeffectsandinhibitsrelapsetodrug-seekingbehavior.

CompoundLibraries

NGB2904isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	530.92
Formula	C₂₈H₂₉Cl₂N₃O.HCl
Storage	Desiccateat+4°C
Purity	≥98%(HPLC)
CASNumber	189061-11-8
PubChemID	19366304
InChIKey	PFIWYJNBKGCVFM-UHFFFAOYSA-N
Smiles	Cl.ClC1=C(Cl)C(=CC=C1)N1CCN(CCCCNC(=O)C2=CC=C3C(CC4=CC=CC=C34)=C2)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	13.27	25
	ethanol	2.65	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight530.92.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.88mL	9.42mL	18.84mL
5mM	0.38mL	1.88mL	3.77mL
10mM	0.19mL	0.94mL	1.88mL
50mM	0.04mL	0.19mL	0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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