Biological Activity
A selective inhibitor of inducible nitric oxide synthase (IC50 = 3.3 μM).
Technical Data
| M. Wt | 223.7 |
| Formula | C8H17N3O2.HCl |
| Storage | Desiccate at -20°C |
| CAS Number | 150403-89-7 |
| PubChem ID | 9794509 |
| InChI Key | HJYWSATZDBEAOS-FJXQXJEOSA-N |
| Smiles | N=C(NCCCC[C@@H](C(O)=O)N)C.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 223.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.47 mL | 22.35 mL | 44.7 mL |
| 5 mM | 0.89 mL | 4.47 mL | 8.94 mL |
| 10 mM | 0.45 mL | 2.24 mL | 4.47 mL |
| 50 mM | 0.09 mL | 0.45 mL | 0.89 mL |
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References
References are publications that support the products' biological activity.
Connor et al (1995) Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur.J.Pharmacol. 273 15 PMID: 7537678
Moore et al (1994) L-N6-(1-Iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J.Med.Chem. 37 3886 PMID: 7525961
Keywords: L-NIL hydrochloride, supplier, Selective, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, iNOS, iNOS, Tocris Bioscience
