Biological Activity
Sodium salt of the non-selective NOS inhibitor 7-nitroindazole (Cat. No. 0602).
Technical Data
| M. Wt | 185.12 |
| Formula | C7H4N3O2Na |
| Storage | Desiccate at -20°C |
| Purity | ≥98% |
| CAS Number | 161467-34-1 |
| PubChem ID | 16760594 |
| InChI Key | DJMLKKIIBMJGIQ-UHFFFAOYSA-N |
| Smiles | [Na+].[O-][N+](=O)C1=C2[N-]N=CC2=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 9.26 | 50 |
Preparing Stock Solutions
The following data is based on the product molecular weight 185.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.4 mL | 27.01 mL | 54.02 mL |
| 5 mM | 1.08 mL | 5.4 mL | 10.8 mL |
| 10 mM | 0.54 mL | 2.7 mL | 5.4 mL |
| 50 mM | 0.11 mL | 0.54 mL | 1.08 mL |
Molarity Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
O'Neill et al (1996) Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia. Eur.J.Pharmacol. 310 115 PMID: 8884206
Silva et al (1995) Increased striatal dopamine efflux in vivo following inhibition of cerebral nitric oxide synthase by the novel monosodium salt of 7-nitroindazole. Br.J.Pharmacol. 114 257 PMID: 7533610
Keywords: 7-NINA, supplier, Non-Selective, NOS, Nitric, Oxide, Signaling, Signalling, iNOS, nNOS, eNOS, NO, Synthases, Non-selective, NOS, Non-selective, NOS, Tocris Bioscience
