Tocris/NKH 477/1603/50/50毫克-免疫在线蚂蚁淘旗下平台

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Tocris/NKH 477/1603/50/50毫克

商品编号： 1603/50

品牌： Tocris Bioscience

市场价： ¥17580.00

美元价： 10548.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Water-solubleadenylylcyclaseactivator

AlternativeNames:Colforsindapropatehydrochloride,6-(3-dimethylaminopropionyl)forskolinhydrochloride

ChemicalName:N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-ylesterβ-alaninehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Water-solubleanalogofforskolin(Cat.No.1099)thatisapotentactivatorofadenylylcyclase;showssomeselectivityforcardiac(typeV)adenylylcyclase.Stimulatesbronchodilation(EC₅₀=32.6nM)andisanorallyactivepotentpositivechronotropeandhypotensiveagentinvivo.AlsoavailableaspartofthePKATocriset™.

TechnicalData

M.Wt	546.1
Formula	C₂₇H₄₃NO₈.HCl
Storage	Desiccateat+4°C
Purity	≥98%(HPLC)
CASNumber	138605-00-2
PubChemID	444028
InChIKey	VIRRLEDAYYYTOD-YHEOSNBFSA-N
Smiles	O=C(CCN(C)C)O[C@H]2[C@@]1([H])C(C)(C)CC[C@H](O)[C@@](C)1[C@]3(O)[C@@](O[C@](C=C)(C)CC3=O)(C)[C@H]2OC(C)=O.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	54.61	100
	ethanol	8.19	15
	water	21.84	40

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight546.1.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.83mL	9.16mL	18.31mL
5mM	0.37mL	1.83mL	3.66mL
10mM	0.18mL	0.92mL	1.83mL
50mM	0.04mL	0.18mL	0.37mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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