Tocris/NNC 711/1779/10/10毫克-免疫在线蚂蚁淘旗下平台

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Tocris/NNC 711/1779/10/10毫克

商品编号： 1779/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：转运体

公司分类： Transporters

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveinhibitorofGAT-1

ChemicalName:1,2,5,6-Tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-3-pyridinecarboxylicacidhydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveinhibitorofGABAuptakebyGAT-1(IC₅₀valuesare0.04,171,1700and622μMforhGAT-1,rGAT-2,hGAT-3andhBGT-1respectively).AnticonvulsantfollowingsystemicadmiNISTrationinvivo.Alsoexhibitscognition-enhancingactivity.

CompoundLibraries

NNC711isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	386.88
Formula	C₂₁H₂₂N₂O₃.HCl
Storage	Desiccateat+4°C
Purity	≥99%(HPLC)
CASNumber	145645-62-1
PubChemID	123738
InChIKey	YZYRTEYMUTWJPL-UHFFFAOYSA-N
Smiles	O=C(C1=CCCN(CCO/N=C(C3=CC=CC=C3)/C2=CC=CC=C2)C1)O.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	38.69	100
	ethanol	3.87	10
	water	3.87	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight386.88.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.58mL	12.92mL	25.85mL
5mM	0.52mL	2.58mL	5.17mL
10mM	0.26mL	1.29mL	2.58mL
50mM	0.05mL	0.26mL	0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

DilutionCalculator

ProductDatasheets