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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/NS 1643/3062/10/10 mg
商品详细Tocris/NS 1643/3062/10/10 mg
Tocris/NS 1643/3062/10/10 mg
Tocris/NS 1643/3062/10/10 mg
商品编号: 3062/10
品牌: Tocris Bioscience
市场价: ¥2580.00
美元价: 1548.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:KV11.1(hERG)channelactivator;antiarrhythmic
ChemicalName:N,N'-Bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Humanether-a-go-gorelatedgene(hERG)KV11.1channelactivator(EC50=10.5μM).ExhibitsdifferentmolecularmechanismsofactionatKV11.1(hERG1)andKV11.2(hERG2)channels.Displaysantiarrhythmicactivityinvitro.

CompoundLibraries

NS1643isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt380.24
FormulaC15H10F6N2O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber448895-37-2
PubChemID10177784
InChIKeyNJFVQMRYJZHGME-UHFFFAOYSA-N
SmilesOC1=C(NC(NC2=C(O)C=CC(C(F)(F)F)=C2)=O)C=C(C(F)(F)F)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO9.5125
ethanol38.02100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight380.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.63mL13.15mL26.3mL
5mM0.53mL2.63mL5.26mL
10mM0.26mL1.31mL2.63mL
50mM0.05mL0.26mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet