Tocris/NS 6180/4864/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/NS 6180/4864/10/10 mg

Tocris/NS 6180/4864/10/10 mg

商品编号： 4864/10

品牌： Tocris Bioscience

市场价： ¥2780.00

美元价： 1668.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentK_Ca3.1channelblocker

ChemicalName:4-[[3-(Trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentK_Ca3.1channelblocker(IC₅₀valuesare9,14and15nMforrat,humanandmouseerythrocyteK_Ca3.1channelsrespectively).Exhibits~50%inhibitionofK_Ca1.1,K_V1.3,andK_V11.1channels,noradrenalineanddopaminetransporters,L-typeCa²⁺channelsandmelatoninreceptorsataconcentrationof10μM.PotentlyinhibitsIL-2andIFN-γproductioninratlymphocytes(IC₅₀~50nM);reducesDBNS-inducedexperimentalcolitisinrats.

TechnicalData

M.Wt	323.33
Formula	C₁₆H₁₂F₃NOS
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	353262-04-1
PubChemID	11837221
InChIKey	ZUIJXKLTUFCDGO-UHFFFAOYSA-N
Smiles	O=C2N(CC3=CC=CC(C(F)(F)F)=C3)C1=CC=CC=C1SC2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	32.33	100
	ethanol	32.33	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight323.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.09mL	15.46mL	30.93mL
5mM	0.62mL	3.09mL	6.19mL
10mM	0.31mL	1.55mL	3.09mL
50mM	0.06mL	0.31mL	0.62mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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