Tocris/NS 8593盐酸盐/4597/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/NS 8593盐酸盐/4597/10/10 mg

Tocris/NS 8593盐酸盐/4597/10/10 mg

商品编号： 4597/10

品牌： Tocris Bioscience

市场价： ¥3700.00

美元价： 2220.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveK_Ca2(SK)channelnegativemodulator;inhibitsSKcurrents

ChemicalName:N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-aminehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveK_Ca2(SK)channelnegativemodulator;inhibitsSKchannelcurrents(K_dvaluesare0.42,0.6and0.73μMforSK1,SK2andSK3respectivelyat0.5μMCa²⁺).ExhibitsselectivityforSKchannelsoverK_Ca1.1(BK),K_Ca3.1(IK),K_v,Na_vandCa_vchannels.Inhibitsafterhyperpolarizationinhippocampalslices.

CompoundLibraries

NS8593hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	299.8
Formula	C₁₇H₁₇N₃.HCl
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	875755-24-1
PubChemID	71311765
InChIKey	VWEKCDTXUUPBNA-PFEQFJNWSA-N
Smiles	C12=CC=CC=C1N=C(N[C@H]3C(C=CC=C4)=C4CCC3)N2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	29.98	100
	ethanol	6	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight299.8.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.34mL	16.68mL	33.36mL
5mM	0.67mL	3.34mL	6.67mL
10mM	0.33mL	1.67mL	3.34mL
50mM	0.07mL	0.33mL	0.67mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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