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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > protease > Tocris/NSC 687852/4566/10/10 mg
商品详细Tocris/NSC 687852/4566/10/10 mg
Tocris/NSC 687852/4566/10/10 mg
Tocris/NSC 687852/4566/10/10 mg
商品编号: 4566/10
品牌: Tocris Bioscience
市场价: ¥2780.00
美元价: 1668.00
产地: 美国(厂家直采)
公司:
产品分类: 蛋白酶类
公司分类: protease
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:InhibitorofUCHL5andUSP14
AlternativeNames:b-AP15
ChemicalName:3,5-Bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propene-1-yl)-4-piperidone
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorof19Sregulatoryparticleassociateddeubiquitinatingenzymes(DUBs),UCHL5andUSP14.ShowsminimalinhibitionofUCHL-1,UCHL-3,USP2,USP7,USP,BAP1andproteasomeactivity.InducesapoptosisbycathepsinD-dependentcaspase-cleavage(IC50=0.5μM).Displaysantitumoractivityinvivo.

TechnicalData

M.Wt419.39
FormulaC22H17N3O6
StorageStoreat+4°C
Purity≥97%(HPLC)
CASNumber1009817-63-3
PubChemID5351435
InChIKeyGFARQYQBWJLZMW-JYFOCSDGSA-N
SmilesO=C(/C(CN(C(C=C)=O)C3)=C/C2=CC=C([N+]([O-])=O)C=C2)/C3=C/C1=CC=C([N+]([O-])=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.94100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight419.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.38mL11.92mL23.84mL
5mM0.48mL2.38mL4.77mL
10mM0.24mL1.19mL2.38mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet