Tocris/NU 7026/2828/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/NU 7026/2828/50/50 mg

Tocris/NU 7026/2828/50/50 mg

商品编号： 2828/50

品牌： Tocris Bioscience

市场价： ¥14100.00

美元价： 8460.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveDNA-PKinhibitor

ChemicalName:2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ATP-competitiveinhibitorofDNA-dependentproteinkinase(DNA-PK).DisplaysselectivityoverotherPIKKfamilyenzymes(IC₅₀valuesare0.23,13.0,>100and>100μMforDNA-PK,PI3K,ATMandATRrespectively).RADIosensitizesbothproliferatingandquiescentmouseembryonicfibroblastcellstoIRandinhibitsDSBrepair.

TechnicalData

M.Wt	281.31
Formula	C₁₇H₁₅NO₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	154447-35-5
PubChemID	9860529
InChIKey	KKTZALUTXUZPSN-UHFFFAOYSA-N
Smiles	O=C2C1=CC=C3C(C=CC=C3)=C1OC(N4CCOCC4)=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	2.81	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight281.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.55mL	17.77mL	35.55mL
5mM	0.71mL	3.55mL	7.11mL
10mM	0.36mL	1.78mL	3.55mL
50mM	0.07mL	0.36mL	0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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