Biological Activity
Deuterated nalmefene (Cat. No. 4085).
Technical Data
| M. Wt | 342.45 |
| Formula | C21H22D3NO3 |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 55096-26-9 |
| PubChem ID | 71750904 |
| InChI Key | WJBLNOPPDWQMCH-TVFUAGGXSA-N |
| Smiles | C=C3[C@H]5[C@]24C1=C(O5)C(O)=CC=C1C[C@@H](N(C([2H])([2H])C6([2H])CC6)CC4)[C@@](O)2CC3 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble in DMSO |
Preparing Stock Solutions
The following data is based on the product molecular weight 342.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.92 mL | 14.6 mL | 29.2 mL |
| 5 mM | 0.58 mL | 2.92 mL | 5.84 mL |
| 10 mM | 0.29 mL | 1.46 mL | 2.92 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.58 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Michel et al (1985) Binding of a new opiate antagonist, nalmefene, to rat brain membranes. Methods Find.Exp.Clin.Pharmacol. 7 175 PMID: 2991678
Wang et al (1998) Nalmefene: a long-acting opioid antagonist. Clinical applications in emergency medicine. J.Emerg.Med. 16 471 PMID: 9610980
Osborn et al (2010) In vivo characterization of the opioid antagonist nalmefene in mice. Life Sci. 86 624 PMID: 20159022
Keywords: Nalmefene - d3, supplier, opioid, receptors, antagonists, deuterated, Miscellaneous/Non-selective, Opioids, Stable, Isotopically, Labeled, Compounds, Miscellaneous/Non-selective, Opioids, Tocris Bioscience
