Biological Activity
Opioid antagonist.
Technical Data
| M. Wt | 377.87 |
| Formula | C20H23NO4.HCl |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 16676-29-2 |
| PubChem ID | 11957643 |
| InChI Key | RHBRMCOKKKZVRY-OGWSAYKTSA-N |
| Smiles | O=C3[C@H]5C24C1=C(O5)C(O)=CC=C1CC(N(CC6CC6)CC4)[C@@](O)2CC3.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 37.79 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 377.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.65 mL | 13.23 mL | 26.46 mL |
| 5 mM | 0.53 mL | 2.65 mL | 5.29 mL |
| 10 mM | 0.26 mL | 1.32 mL | 2.65 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.53 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Gold et al (1982) Naltrexone, opiate addiction, and endorphins. Med.Res.Rev. 2 211 PMID: 6289026
Tempel et al (1982) Supersensitivity of brain opiate receptor subtypes after chronic naltrexone treatment. Life Sci. 31 1401 PMID: 6292636
Zukin et al (1982) Naltrexone-induced opiate receptor supersensitivity. Brain Res. 245 285 PMID: 6289965
Keywords: Naltrexone hydrochloride, supplier, Broad, spectrum, antagonists, Opioids, Receptors, Miscellaneous/Non-selective, Opioids, Miscellaneous/Non-selective, Opioids, Tocris Bioscience
