Tocris/Nepicastat盐酸盐/5037/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Nepicastat盐酸盐/5037/50/50 mg

Tocris/Nepicastat盐酸盐/5037/50/50 mg

商品编号： 5037/50

品牌： Tocris Bioscience

市场价： ¥13300.00

美元价： 7980.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentandselectivedopamineβ-hydroxylase(DBH)inhibitor;orallybioavailable

ChemicalName:5-(Aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thionehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivedopamineβ-hydroxylase(DBH)inhibitor(IC₅₀=9nM).SelectiveforDBHover12otherenzymes.Decreasesnoradrenalineandincreasesdopaminelevelsintissuesandplasmainhypertensiverats.Preventsprogressiveleftventriculardysfunctioninaninvivoheartfailuremodel.Alsopotentiatesthestimuluseffectsofcocainewithoutproducingcocaine-likeeffectsinrats.Orallybioavailable.

TechnicalData

M.Wt	331.81
Formula	C₁₄H₁₅F₂N₃S.HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	170151-24-3
PubChemID	9840545
InChIKey	DIPDUAJWNBEVOY-PPHPATTJSA-N
Smiles	S=C(NC=C3CN)N3[C@H]2CCC1=C(F)C=C(F)C=C1C2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	33.18	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight331.81.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.01mL	15.07mL	30.14mL
5mM	0.6mL	3.01mL	6.03mL
10mM	0.3mL	1.51mL	3.01mL
50mM	0.06mL	0.3mL	0.6mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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