Biological Activity
Neuropeptide Y2 receptor agonist.
Technical Data
| M. Wt | 2983 |
| Formula | C135H209N41O36 |
| Sequence |
PAEDLARYYSALRHYINLITRQRY (Modifications: Tyr-24 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 113662-54-7 |
| PubChem ID | 16142386 |
| InChI Key | HEALDAASUSTTPJ-QGTLAHJGSA-N |
| Smiles | [H]N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 0.80 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 2983. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.34 mL | 1.68 mL | 3.35 mL |
| 5 mM | 0.07 mL | 0.34 mL | 0.67 mL |
| 10 mM | 0.03 mL | 0.17 mL | 0.34 mL |
| 50 mM | 0.01 mL | 0.03 mL | 0.07 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Aguirre et al (1990) Centrally injected neuropeptide Y (13-36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1-36) in the awake male rat. Neurosci.Lett. 118 5 PMID: 2259468
Aguirre et al (1995) Increased vasopressor actions of intraventricular neuropeptide Y-(13-36) in spontaneously hypertensive versus normotensive Wistar-Kyoto rats. Possible relationship to increases in Y2 receptor binding in the nucleus tractus solitarius. Brain Res. 684 159 PMID: 7583217
Martire et al (1993) Region-specific inhibition of potassium-evoked [3H]noradrenaline release from rat brain synaptosomes by neuropeptide Y-(13-36). Involvement of NPY receptors of the Y2 type. Eur.J.Pharmacol. 230 231 PMID: 8422905
Keywords: Neuropeptide Y 13-36 (porcine), supplier, Y2, receptor, agonists, Neuropeptides, Y, Receptors, NPY, NeuropeptideY, (porcine), 13-36, NPY1336, NPY, 13-36, (porcine), NPY, Receptors, NPY, Receptors, Tocris Bioscience
