Tocris/Nilvadipine/5711/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Nilvadipine/5711/50/50 mg

Tocris/Nilvadipine/5711/50/50 mg

商品编号： 5711/50

品牌： Tocris Bioscience

市场价： ¥1980.00

美元价： 1188.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Sykkinaseinhibitor;inhibitsAβproduction

ChemicalName:2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid3-methyl5-(1-methylethyl)ester

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Sykinhibitor.BlocksAβproduction,APPβsecretionandreducesBACE-1expressioninCHOcellsover-expressingAβinvitro.EnhancesclearanceofAβacrossthebloodbrainbarrierinvivo.ReducesbrainAβlevelsinamousetauopathymodel.AlsoL-typecalciumchannelblockerandantihypertensive.

TechnicalData

M.Wt	385.37
Formula	C₁₉H₁₉N₃O₆
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	75530-68-6
PubChemID	4494
InChIKey	FAIIFDPAEUKBEP-UHFFFAOYSA-N
Smiles	O=C(OC)C1=C(C#N)NC(C)=C(C(OC(C)C)=O)C1C2=CC([N+]([O-])=O)=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	38.54	100
	ethanol	19.27	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight385.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.59mL	12.97mL	25.95mL
5mM	0.52mL	2.59mL	5.19mL
10mM	0.26mL	1.3mL	2.59mL
50mM	0.05mL	0.26mL	0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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