Biological Activity
Endogenous peptide derived from the same prepropeptide as ghrelin. Reported to suppress food intake and reduce body weight-gain in rats.
Technical Data
| M. Wt | 2546.86 |
| Formula | C116H176N32O33 |
| Sequence |
FNAPFDVGIKLSGVQYQQHSQAL (Modifications: Leu-23 = C-terminal amide) |
| Storage | Store at -20°C |
| CAS Number | 1081110-72-6 |
| PubChem ID | 91826105 |
| InChI Key | IXQOGPZNKNSCJR-QQDMDDJXSA-N |
| Smiles | [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 1 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 2546.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.39 mL | 1.96 mL | 3.93 mL |
| 5 mM | 0.08 mL | 0.39 mL | 0.79 mL |
| 10 mM | 0.04 mL | 0.2 mL | 0.39 mL |
| 50 mM | 0.01 mL | 0.04 mL | 0.08 mL |
Molarity Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Tang et al (2008) Obestatin: its physicochemical characteristics and physiological functions. Peptides 29 639 PMID: 18325633
Zhang et al (2005) Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 310 996 PMID: 16284174
Keywords: Obestatin (human), supplier, Endogenous, anorexigenic, peptide, Peptide, Receptor, Receptors, GPR39, Other, Peptide, Receptors, Other, Peptide, Receptors, Tocris Bioscience
