Tocris/FPS ZM1/6237/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/FPS ZM1/6237/50/50 mg

Tocris/FPS ZM1/6237/50/50 mg

商品编号： 6237/50

品牌： Tocris Bioscience

市场价： ¥5500.00

美元价： 3300.00

产地：美国(厂家直采)

公司：

产品分类：其他试剂

公司分类： Other_reagents

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:HighaffinityantagoNISTofRAGE

ChemicalName:4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highaffinityantagonistofthereceptorforadvancedglycationendproducts(RAGE)(K_i=25nM).BlocksAβbindingtotheVdomainofRAGEandinhibitsAβ40-andAβ42-inducedcellularstressinRAGE-expressingcellsinvitroandinthemousebraininvivo.Blocksβ-secretaseactivity,Aβproduction,microgliaactivationandneuroinflammationinvivo.BBBpermeable.

TechnicalData

M.Wt	327.85
Formula	C₂₀H₂₂ClNO
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	945714-67-0
PubChemID	24752728
InChIKey	XDFKWGIBQMHSOH-UHFFFAOYSA-N
Smiles	ClC1=CC=C(C(N(C2CCCCC2)CC3=CC=CC=C3)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	32.78	100
	ethanol	32.78	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight327.85.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.05mL	15.25mL	30.5mL
5mM	0.61mL	3.05mL	6.1mL
10mM	0.31mL	1.53mL	3.05mL
50mM	0.06mL	0.31mL	0.61mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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