Biological Activity
Muscarinic agonist.
Compound Libraries
Oxotremorine sesquifumarate is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 380.4 |
| Formula | C12H18N2O.1.5C4H4O4 |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 17360-35-9 |
| PubChem ID | 6436473 |
| InChI Key | WLYYOFJEBGHKEC-VQYXCCSOSA-N |
| Smiles | OC(=O)C=CC(O)=O.OC(=O)C=CC(O)=O.OC(=O)C=CC(O)=O.O=C1CCCN1CC#CCN1CCCC1.O=C1CCCN1CC#CCN1CCCC1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| phosphate buffered saline | 9.51 | 25 | |
| DMSO | 38.04 | 100 | |
| water | 9.51 | 25 |
Preparing Stock Solutions
The following data is based on the product molecular weight 380.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.63 mL | 13.14 mL | 26.29 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
| 10 mM | 0.26 mL | 1.31 mL | 2.63 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.53 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Fisher et al (1984) Differential stimulation in inositol phospholipid turnover in brain by analogs of oxotremorine. J.Neurochem. 43 1171 PMID: 6088696
Moroi-Fetters et al (1988) Muscarinic receptor-mediated phosphoinositide hydrolysis in the rat retina. J.Pharmacol.Exp.Ther. 246 553 PMID: 2841451
Merck Index 12 7085 PMID:
Keywords: Oxotremorine sesquifumarate, supplier, Muscarinic, agonist, Receptors, Acetylcholine, ACh, Non-selective, Muscarinics, Non-selective, Muscarinics, Tocris Bioscience
