Biological Activity
Neurohypophyseal peptide. Stimulates uterine contraction and lactation.
Technical Data
| M. Wt | 1007.19 |
| Formula | C43H66N12O12S2 |
| Sequence |
CYIQNCPLG (Modifications: Gly-9 = C-terminal amide, Disulfide bridge between 1 - 6) |
| Storage | Desiccate at -20°C |
| CAS Number | 50-56-6 |
| PubChem ID | 439302 |
| InChI Key | XNOPRXBHLZRZKH-DSZYJQQASA-N |
| Smiles | [H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC1=O)[C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 1 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 1007.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.99 mL | 4.96 mL | 9.93 mL |
| 5 mM | 0.2 mL | 0.99 mL | 1.99 mL |
| 10 mM | 0.1 mL | 0.5 mL | 0.99 mL |
| 50 mM | 0.02 mL | 0.1 mL | 0.2 mL |
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References
References are publications that support the products' biological activity.
Barberis and Tribolle (1996) Vasopressin and oxytocin receptors in the central nervous system. Crit.Rev.Neurobiol. 10 119 PMID: 8853957
Thibonnier et al (1998) Signal transduction pathways of the human V1-vascular V2-renal, V3-pituitary vasopressin and oxytocin receptors. Prog.Brain Res. 119 147 PMID: 10074787
Keywords: Oxytocin, supplier, Involved, uterine, contraction, lactation, OT, Receptors, agonists, Oxytocin, Receptors, Oxytocin, Receptors, Tocris Bioscience
