Tocris/P005091/4733/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/P005091/4733/50/50 mg

Tocris/P005091/4733/50/50 mg

商品编号： 4733/50

品牌： Tocris Bioscience

市场价： ¥14100.00

美元价： 8460.00

产地：美国(厂家直采)

公司：

产品分类：蛋白酶类

公司分类： protease

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:USP7inhibitor

ChemicalName:1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveinhibitorofubiquitin-specificprotease(USP)7(IC₅₀=4.2μM).Displayslittle-to-noinhibitionofotherUSPvariantsorproteasessuchascaspase,cathepsinsandserineproteases;exhibitssomeactivityatUSP47.Induceselevatedp53andapoptosisincancercelllines;displaysantiangiogenicactivityinvivo.

TechnicalData

M.Wt	348.22
Formula	C₁₂H₇Cl₂NO₃S₂
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	882257-11-6
PubChemID	2819993
InChIKey	LKZLGMAAKNEGCH-UHFFFAOYSA-N
Smiles	CC(=O)C1=CC(=C(SC2=CC=CC(Cl)=C2Cl)S1)[N+]([O-])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	3.48	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight348.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.87mL	14.36mL	28.72mL
5mM	0.57mL	2.87mL	5.74mL
10mM	0.29mL	1.44mL	2.87mL
50mM	0.06mL	0.29mL	0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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