Tocris/PAC 1/2581/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PAC 1/2581/10/10 mg

Tocris/PAC 1/2581/10/10 mg

商品编号： 2581/10

品牌： Tocris Bioscience

市场价： ¥2780.00

美元价： 1668.00

产地：美国(厂家直采)

公司：

产品分类：蛋白酶类

公司分类： protease

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Activatorofprocaspase-3;pro-apoptotic

ChemicalName:4-(Phenylmethyl)-1-piperazineaceticacid[[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Procaspase-activatingcompound;activatesprocaspase-3toproducecaspase-3(EC₅₀=0.22μM).Alsoactivatesprocaspase-7inalessefficientmanner(EC₅₀=4.5μM).Pro-apoptotic;inducesapoptosisinbothcancerousandnon-cancerouscellsdependentonprocaspase-3concentration(IC₅₀valuesare0.003-1.41and5.02-9.98μMrespectively).

CompoundLibraries

PAC1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	392.5
Formula	C₂₃H₂₈N₄O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	315183-21-2
PubChemID	9675990
InChIKey	YQNRVGJCPCNMKT-LFVJCYFKSA-N
Smiles	O=C(N/N=C/C3=CC=CC(CC=C)=C3O)CN(CC2)CCN2CC1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	29.44	75
	DMSO	39.25	100
	ethanol	19.63	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight392.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.55mL	12.74mL	25.48mL
5mM	0.51mL	2.55mL	5.1mL
10mM	0.25mL	1.27mL	2.55mL
50mM	0.05mL	0.25mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets